发明名称 |
FOUR BRANCHED DENDRIMER-PEG FOR CONJUGATION TO PROTEINS AND PEPTIDES |
摘要 |
A polymeric dendrimer-like structure with four branches of monomethoxy-polyethylene glycol that can be represented as: The carboxylic group of the previous structure can be functionalized for the production of conjugates of pharmaceutical interest. The binding of this dendrimer-like polyethylene glycol to therapeutic proteins improves their in vitro and in vivo stability.
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申请公布号 |
US2009082537(A1) |
申请公布日期 |
2009.03.26 |
申请号 |
US20060095335 |
申请日期 |
2006.11.20 |
申请人 |
RAMON HERNANDEZ JOSE ANGEL;CASTRO ODIO FEDEL RAUL;SAEZ MARTINEZ VIVIAN MARIA;PAEZ MEIRELES ROLANDO;FERNANDEZ SANCHEZ EDUARDO |
发明人 |
RAMON HERNANDEZ JOSE ANGEL;CASTRO ODIO FEDEL RAUL;SAEZ MARTINEZ VIVIAN MARIA;PAEZ MEIRELES ROLANDO;FERNANDEZ SANCHEZ EDUARDO |
分类号 |
C12N9/70;C07K14/475;C07K14/485;C07K14/56;C08G65/22 |
主分类号 |
C12N9/70 |
代理机构 |
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