| 摘要 |
A substrate includes: a base material; and chelators which are three dimensionally covalently bound to the base material at a density of 7.8x1015/mm3 or greater and 4.5x1017/mm3 or less, or two dimensionally covalently bound to the base material at a planar density of 2.0x1011/mm2 or greater and 1.0x1013/mm2 or less. Metal ions are coordinately bound to the chelators, and a bioactive substance having histidine tags are coordinately bound to the metal ions. A blocking agent having ligand sets are coordinately bound to the metal ions to which the bioactive substance is not coordinately bound.
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