发明名称 GLUCOLIPID DERIVATIVE, ITS MANUFACTURING METHOD AND MEDICINE CONTAINING IT AS EFFECTIVE COMPONENT
摘要 PROBLEM TO BE SOLVED: To provide a glucolipid derivative having anα-S-glucosidic linkage which is useful as an antitumor medicine and an immunopotentiator, and its manufacturing method, and medicines containing it as an effective component. SOLUTION: This glucolipid derivative is a compound represented by general formula (I) (wherein W is a 9-17C saturated or unsaturated carbon chain and further in some case contains a hydroxy group, X is an 11-25C saturated or unsaturated carbon chain and further in some case contains a hydroxy group, Y represents -S(O)<SB>0-2</SB>CH<SB>2</SB>-, Z represents -CO- or -SO<SB>2</SB>-, R represents -CH<SB>2</SB>OH, -CO<SB>2</SB>H, -CO<SB>2</SB>OCH<SB>2</SB>CO<SB>2</SB>H, or -CH<SB>2</SB>OSO<SB>3</SB>H group, and R<SB>0</SB>represents -OH, -NH<SB>2</SB>, or -NHAc group), or its pharmaceutically permissible salts. COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009062381(A) 申请公布日期 2009.03.26
申请号 JP20080263962 申请日期 2008.10.10
申请人 KOTOBUKI SEIYAKU KK 发明人 TOMIYAMA YASUSHI;YANAGISAWA TAKASHI;FUTAMURA MASAYUKI;NODA ATSUSHI;TOMIYAMA TAKESHI
分类号 C07D309/10;A61K31/351;A61P35/00;A61P35/04;A61P37/04 主分类号 C07D309/10
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