发明名称 |
PHARMACEUTICAL COMPOSITION FOR TREATING CANCER |
摘要 |
The present invention provides a small interfering RNA (siRNA) that is capable of inhibiting intracellular expression of Wnt1 through complementary binding to a Wnt1 transcript (mRNA transcript) base sequence and a pharmaceutical composition for treating cancer comprising the same. siRNA of the present invention which is complementary to a base sequence of a Wnt1 transcript (mRNA) provides apoptotic cancer cell death due to inhibition of expression of Wnt1 commonly expressed in cancer cells, by RNA-mediated interference (RNAi). Therefore, the composition of the present invention comprising the same can be used as an excellent anticancer drug.
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申请公布号 |
US2009081282(A1) |
申请公布日期 |
2009.03.26 |
申请号 |
US20080234271 |
申请日期 |
2008.09.19 |
申请人 |
KOREA UNIVERSITY INDUSTRIAL & ACADEMIC COLLABORATION FOUNDATION |
发明人 |
OH YU-KYOUNG;SHIM GA YONG;KIM SANG-HEE |
分类号 |
A61K31/7105;A61K9/127;A61P35/00 |
主分类号 |
A61K31/7105 |
代理机构 |
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地址 |
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