<p>Machine for cleaning at least one shoe (2) comprising at least one seat (9) for the shoe (2), a pair of cleaning elements (11) arranged substantially in correspondence of the seat (9), driving means (10) of the cleaning elements (11) and of the gripping and supporting means (34) of the shoe (2) to lock the shoe in the seat (9); the cleaning elements (11) are movable around said seat (9) along a predetermined path (P) so as to affect the shoe (2), in particular the outer surface of the same.</p>