摘要 |
Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-choleslerol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1 В or Ris a phenyl group which has an ortho aryl, heterocyclic, benzoheterocyclic or benzocycloalkyl substituent, and one other position on the 5 membered ring has an aromalic, helerocyclic, cycloalkyl, benzoheterocyclic or benzocycloalkyl substituent connected directly to the ring or attached to the ring through a -CH-.І |