发明名称 CETP INHIBITORS
摘要 Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-choleslerol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1 В or Ris a phenyl group which has an ortho aryl, heterocyclic, benzoheterocyclic or benzocycloalkyl substituent, and one other position on the 5 membered ring has an aromalic, helerocyclic, cycloalkyl, benzoheterocyclic or benzocycloalkyl substituent connected directly to the ring or attached to the ring through a -CH-.І
申请公布号 UA86077(C2) 申请公布日期 2009.03.25
申请号 UA20070001058 申请日期 2005.07.01
申请人 MERCK & CO., INC. 发明人 ALI AMJAD;NAPOLITANO JOANN M.;DENG QIAOLIN;LU ZHIJIAN;SINCLAIR PETER J;TAYLOR GAYLE E.;THOMPSON CHRISTOPHER F.;QURAISHI NAZIA;SMITH CAMERON J.;HUNT JULIANNE A.
分类号 C07D263/20;A61K31/4015;A61K31/4166;A61K31/433;A61K31/4439;A61P3/06;C07D207/26;C07D233/24;C07D263/22;C07D285/10;C07D401/04;C07D413/04;C07D413/06 主分类号 C07D263/20
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