发明名称 |
Novel hepatocyte-like cells and hepatoblast-like cells derived from hbs cells |
摘要 |
The present invention relates to a novel hepatocyte-like cell population derived from hBS cells and to the potential use of such heopatocyte-like cells in e.g. medical treatment, drug screening and toxicity testing. Furthermore, the invention relates to hepatoblast-like cells that may have suitable characteristics so that they can be used for the same applications as the hepatocyte-like cells and that furthermore may be used in in vitro studies of hepatogenesis such as early hepatogenesis or hepato-regenerative disorders. Both the hepatocyte-like and the hepatoblast-like cells according to the invention express drug transporter and/or drug metabolising characteristics either at the gene or protein expression level. |
申请公布号 |
GB2453068(A) |
申请公布日期 |
2009.03.25 |
申请号 |
GB20080022449 |
申请日期 |
2007.06.04 |
申请人 |
CELLARTIS AB |
发明人 |
NICO HEINS;BARBARA KUEPPERS-MUNTHER;JOSEFINA EDSBAGGE |
分类号 |
A61K35/407;A61P1/16;C12N5/071;C12N5/074;G01N33/50 |
主分类号 |
A61K35/407 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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