| 发明名称 |
N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES |
| 摘要 |
Disclosed are compounds of the formula (I), wherein the variables R, R, R, R, R, and Rare as defined herein. These compounds have activity as inhibitors of betasecretase and are therefore useful in treating a variety of discorders such as Alzheimer's Disease.(І) |
| 申请公布号 |
UA85994(C2) |
申请公布日期 |
2009.03.25 |
| 申请号 |
UA20040604411 |
申请日期 |
2002.11.08 |
| 申请人 |
ELAN PHARMACEUTICALS, INC.;PHARMACIA & UPJOHN COMPANY |
发明人 |
JOHN VARGHESE;MAILLARD MICHEL;JAGODZINSKA BARBARA;BECK JAMES P;GAILUNAS ANDREA;FANG LARRY;SEALY JENNIFER;TENBRINK RUTH;FRESKOS JOHN;MICKELSON JOHN;SAMALA LAKSHMAN;HOM ROY |
| 分类号 |
C07D295/16;A61K;A61K31/164;A61K31/18;A61K31/27;A61K31/336;A61K31/341;A61K31/357;A61K31/36;A61K31/381;A61K31/39;A61K31/40;A61K31/41;A61K31/415;A61K31/416;A61K31/4164;A61K31/421;A61K31/423;A61K31/426;A61K31/427;A61K31/428;A61K31/437;A61K31/439;A61K31/4402;A61K31/4409;A61K31/4418;A61K31/4439;A61K31/445;A61K31/455;A61K31/47;A61K31/495;A61P25/28;C07C;C07C217/58;C07C233/36;C07C233/40;C07C233/58;C07C233/78;C07C235/20;C07C235/50;C07C235/74;C07C237/04;C07C237/06;C07C237/08;C07C237/22;C07C237/42;C07C251/38;C07C255/58;C07C271/28;C07C271/44;C07C311/08;C07C311/16;C07C311/17;C07C311/18;C07C311/19;C07C311/20;C07C311/21;C07C311/29;C07C311/37;C07C317/44;C07C317/46;C07C317/50;C07C323/60;C07C323/62;C07C323/65;C07D207/06;C07D207/08;C07D207/14;C07D207/26;C07D207/267;C07D207/48;C07D209/08;C07D211/10;C07D211/44;C07D211/58;C07D211/60;C07D211/96;C07D213/36;C07D213/56;C07D213/64;C07D213/81;C07D213/82;C07D213/89;C07D215/54;C07D217/08;C07D217/22;C07D231/14;C07D231/56;C07D233/64;C07D233/84;C07D233/90;C07D239/34;C07D239/48;C07D241/08;C07D241/24;C07D261/08;C07D263/06;C07D263/34;C07D263/56;C07D265/36;C07D271/06;C07D271/12;C07D277/20;C07D277/30;C07D277/56;C07D285/06;C07D295/155;C07D295/185;C07D295/192;C07D295/22;C07D295/26;C07D307/20;C07D307/46;C07D307/52;C07D309/12;C07D311/58;C07D317/68;C07D333/20;C07D333/22;C07D333/32;C07D333/34;C07D333/58;C07D333/72;C07D403/04;C07D413/04;C07D413/06;C07D413/12;C07D417/04;C07D417/12;C07D471/04;C07D495/04 |
主分类号 |
C07D295/16 |
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