发明名称 |
Nanoparticulate and controlled release compositions comprising aryl-heterocyclic compounds |
摘要 |
The present invention provides a composition comprising ziprasidone useful in the treatment and prevention of schizophrenia and similar psychiatric disorders. In one embodiment, the composition comprises nanoparticulate particles comprising ziprasidone and at least one surface stabilizer. The nanoparticulate particles have an effective average particle size of less than about 2000 nm. In another embodiment, the composition comprises a modified release composition that, upon administration to a patient, delivers ziprasidone in a bimodal, multimodal or continuous manner. The invention also relates to dosage forms containing such compositions, and to methods for the treatment and prevention of schizophrenia and similar psychiatric disorders. |
申请公布号 |
ZA200710715(B) |
申请公布日期 |
2009.03.25 |
申请号 |
ZA20070010715 |
申请日期 |
2007.12.10 |
申请人 |
ELAN PHARMA INTERNATIONAL LIMITED |
发明人 |
DEVANE, JOHN;STARK, PAUL;FANNING, NIALL;REKHI, GURVINDER, SINGH;JENKINS, SCOTT;LIVERSIDGE, GARY |
分类号 |
A61K |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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