发明名称 |
CANCER THERAPY USING BCL-XL-SPECIFIC SINA |
摘要 |
The invention relates to a double-stranded short interfering nucleic acid (siNA) molecule specific to the Bcl-XL transcript, comprising a sense and an antisense region, wherein the sense region comprises the nucleotide sequence SEQ ID NO: 1 or a sequence having at least 70% identity, preferably at least 80% identity, more preferably at least 90% identity with said sequence, and the antisense region comprises a nucleotide sequence that is complementary to the sense region, and its use for treating cancer. |
申请公布号 |
EP2038414(A2) |
申请公布日期 |
2009.03.25 |
申请号 |
EP20070804961 |
申请日期 |
2007.06.22 |
申请人 |
CENTRE REGIONAL DE LUTTE CONTRE LE CANCER - CENTRE FRANCOIS BACLESSE |
发明人 |
POULAIN, LAURENT;GAUDUCHON, PASCAL;BROTIN, EMILIE;SAISON-BEHMOARAS, ESTER |
分类号 |
A61K31/713;A61P35/00;C12N5/10;C12N15/11;C12N15/113 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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