发明名称 |
CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS |
摘要 |
The present invention relates to compounds that bind to chemokine receptors, and having the formula wherein each A, X, Y, R<SUP>1</SUP>, R<SUP>2 </SUP>and R<SUP>3 </SUP>are substituents. The present invention also relates to methods of using such compounds, such as in treating HIV infection and inflammatory conditions such as rheumatoid arthritis. Furthermore, the present invention relates to methods to elevate progenitor and stem cell counts, as well as methods to elevate white blood cell counts, using such compounds. |
申请公布号 |
EP1613613(A4) |
申请公布日期 |
2009.03.25 |
申请号 |
EP20040759481 |
申请日期 |
2004.04.12 |
申请人 |
ANORMED INC. |
发明人 |
BRIDGER, GARY, J.;MCEACHERN, ERNEST, J.;SKERLJ, RENATO;SCHOLS, DOMINIQUE;BAIRD, IAN;KALLER, AL;HARWIG, CURTIS;ZHU, YONGBAO;CHEN, GANG;SKUPINSKA, KRYSTYNA |
分类号 |
C07D401/02;A61K31/44;A61K31/47;C07D213/38;C07D213/61;C07D213/65;C07D213/69;C07D213/70;C07D213/73;C07D213/74;C07D213/75;C07D213/76;C07D213/80;C07D213/82;C07D213/89;C07D401/12;C07D401/14;C07D409/14;C07D413/14;C07D417/12;C07D417/14;C07D451/04;C07D471/06 |
主分类号 |
C07D401/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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