摘要 |
The tumor-inhibiting compounds, verrucarin A and J (Muconomycin A and B) isolated from Myrothecium sp., find use in the inhibition of growth of cancer cells. Verrucarin A and verrucarin J were applied to inhibit the growth of human hepatic cancer cell lines Hep3B and HepG2, human lung cancer cell line A549, and human prostate cancer cell lines LNCaP and DU-145. The compound(s) can further be used as pharmaceutical compositions for inhibition of cancers including hepatic cancer, lung cancer and prostate cancer. |