| 摘要 |
The present invention provides lysine based compounds of the formula (I), and when the compound of formula (I) comprises an amino group, pharmaceutically acceptable ammonium sails thereof, wherein Rmay be, for example (HO)P(O)-, (NaO)P(O)-, alkyl-CO- or cycloalkyl-CO-, wherein X may be, for example, F, Cl and Br, and wherein Rand Rare as defined herein. These lysine based compounds have a physiologically cleavable unit, namely R, whereby upon cleavage of the unit, an HIV aspartyl protease inhibitor is released.(І) |
