发明名称 NOVEL TRICYCLIC SPIROPIPERIDINE COMPOUNDS, THEIR SYNTHESIS AND THEIR USES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY
摘要 Compounds of formula (I) wherein R1, R3, R4, R5, R6, R7, and R10 are as defined in the specification, are described. The present invention also relates to pharmaceutical composition comprising said compounds and to the use of said compounds in therapy. The present invention further relates to processes for the preparation of said compounds and to new intermediates useful in the preparation thereof. Beside, the invention relates to salts and polymorphic forms of the new compounds as well as the preparation thereof.
申请公布号 KR20090030347(A) 申请公布日期 2009.03.24
申请号 KR20097003296 申请日期 2009.02.18
申请人 ASTRAZENECA AB 发明人 ELKINS BARRY;ENNIS DAVID;ERIKSSON TOMAS;GIBSON SCOTT;GU ERIC;HASSALL IAN;HEMMERLING MARTIN;JOSEFSSON BO GOERAN;IVANOVA SVETLANA;KAVITAKE SANTOSH;KUMAR SYTHANA SURESH;KUMAR VINOD;LINGESHA SIDDA;MENSONIDES HARSEMA MARGUERITE;MERIFIELD ERIC;MO JOHN;PAVEY JOHN;PIMM AUSTEN;REUBERSON JAMES;ROGERS MIKE;SCHULZ HAKAN;STRANDBERG PER;ZHENGYU WANG;COOPER MARTIN
分类号 C07D491/107;A61K31/438;A61P11/00;C07C235/60 主分类号 C07D491/107
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