发明名称 PHARMACEUTICAL COMPOUNDS.
摘要 Compounds of Formulae Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia and Ib for <i>in vitro</i>, <i>in situ</i>, and <i>in vivo</i> diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
申请公布号 MX2008013584(A) 申请公布日期 2009.03.23
申请号 MX20080013584 申请日期 2007.04.24
申请人 GENENTECH, INC. 发明人 BING-YAN ZHU;ADRIAN FOLKES.;NAN CHI WAN;ALAN OLIVERO;GEORGETTE CASTANEDO;JANET GUNZNER;TIM HEFFRON;SIMON MATHIEU;DANIEL P. SUTHERLIN;STEPHEN SHUTTLEWORTH;SALLY OXENFORD;IRINA CHUCKOWREE;RICHARD GOLDSMITH
分类号 C07D491/04;A61K31/5025;A61P35/00;C07D495/04;C07D519/00 主分类号 C07D491/04
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