发明名称 |
PROCESS FOR PREPARING POWDER COMPRISING NANOPARTICLES OF SPARINGLY SOLUBLE DRUG |
摘要 |
A manufacturing method of powder including nano particles of insoluble drug is provided to maintain stability in case that insoluble drug is re-dispersed at aqueous solution, to be no side effect by impurity and to improve bio-availability. A manufacturing method of powder including nano particles of insoluble drug comprises steps of: adding particles of insoluble drug which is active component, a surface passivating agent and additional dispersion secondary particle in aqueous solution including dispersion secondary particle to aturation concentration; mixing, shattering and homogenizing the obtained dispersed solution; and centrifuging or filtering the homogenized dispersed solution and drying it and obtaining the powder from the dispersed solution.
|
申请公布号 |
KR20090027734(A) |
申请公布日期 |
2009.03.17 |
申请号 |
KR20097001187 |
申请日期 |
2009.01.20 |
申请人 |
AMOREPACIFIC CORPORATION |
发明人 |
BAE, JOON HO;LEE, JONG HWI;LEE, HYEOK;KIM, JUNG JU |
分类号 |
A61K9/14;A61K9/10 |
主分类号 |
A61K9/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|