发明名称 Method and composition for treatment of renal failure with antibodies and their equivalents as partial or complete replacement for dialysis
摘要 A method for treating patients with renal failure includes administering to them an effective amount of antibody or of a functional equivalent thereof to at least two of urea, creatinine, tumor necrosis factor alpha, interferon gamma, interleukin 6 and interleukin 1 beta. Soluble cytokine receptors also can be employed. The method can be used as a supplement to or as partial or complete replacement for dialysis. A pharmaceutical composition includes antibody or functional equivalent thereof to urea, creatinine, or both; antibody, functional equivalent or soluble cytokine receptor to tumor necrosis factor alpha, interferon gamma, interleukin 6, interleukin 1 beta or any combination thereof The composition can be included in a kit.
申请公布号 US7504106(B2) 申请公布日期 2009.03.17
申请号 US20060375378 申请日期 2006.03.14
申请人 SKURKOVICH BORIS;MILLSTEIN ELLEN;SKURKOVICH SIMON 发明人 SKURKOVICH BORIS;MILLSTEIN ELLEN;SKURKOVICH SIMON
分类号 A61K39/395;A01N37/18;A61K39/00;C07K16/00;C12P21/08;G01N33/53 主分类号 A61K39/395
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