AN ENANTIOSELECTIVE SYNTHESIS OF PYRROLIDINE-SUBSTITUTED FLAVONES.
摘要
<p>The present invention relates to an enantioselective synthesis of (+)-<i>trans</i> enantiomer of pyrrolidines substituted with flavones, represented by Formula 1 or salts thereof, which are inhibitors of cyclin dependant kinases and can be used for treatment of proliferative disorders such as cancer. wherein Ar has the meaning as indicated in the claims.</p>