DOUBLESTRANDED RNA (DSRNA) FOR INHIBITION THE EXPRESSION OF A DEFINED GENE

摘要

A new method to inhibit the expression of a predetermined target gene in a cell, comprises introducing an oligoribonucleotide with double stranded structure (dsRNA) or a vector coding for the dsRNA into the cell, where a strand of the dsRNA is at least in part complementary to the target gene. - ACTIVITY : Antiviral; cytostatic; anti-prion. - MECHANISM OF ACTION : Double stranded RNA inhibitor of gene expression.