METHODS AND COMPOSITIONS FOR THE SIZE-SPECIFIC SEPERATION OF NUCLEIC ACID FROM A SAMPLE

摘要

Provided herein are methods and kits for the separation, extraction and enrichment of short- stranded nucleic acid in the presence of a high background of long-stranded genomic material (e.g., host or maternal nucleic acids). The methods rely on primers that selectively bind to the long- stranded nucleic acid, whereby the primers may be used to subsequently separate the long and short nucleic acid.