发明名称 IMMUNOLOGICAL ASSAY FOR PLASMIN-DIGESTED PRODUCTS OF STABILIZED FIBRIN
摘要 A method of immunologically analyzing plasmin-digested products of stabilized fibrin, characterized by using a combination of a monoclonal antibody (a) which does not react with stabilized fibrin, fibrinogen, and plasmin-digested products of fibrinogen, but reacts with a neoantigen which is newly exposed in a D domain by digesting stabilized fibrin with plasmin, and a monoclonal antibody (b) which recognizes a site different from that recognized by the monoclonal antibody (a), and specifically reacts with plasmin-digested products of stabilized fibrin, wherein one of the monoclonal antibodies (a) and (b) is carried on a magnetic particle, and the other is labeled with an enzyme, and a chemiluminescent substrate is used as a substrate for the enzyme, is disclosed.
申请公布号 US2009068682(A1) 申请公布日期 2009.03.12
申请号 US20060912474 申请日期 2006.04.27
申请人 MITSUBISHI KAGAKU IATRON, INC. 发明人 MATSUYA TAKESHI
分类号 G01N33/53 主分类号 G01N33/53
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