发明名称 |
Methods and reagents for the enhancement of virus transduction in the bladder epithelium |
摘要 |
Agents and methods for enhancing recombinant virus transduction in the bladder epithelium are described. A first method involves contacting the luminal surface of the bladder with a composition comprising a transduction enhancing agent and an oncolytic virus. Alternatively, the luminal surface of the bladder can be contacted first with a pretreatment composition comprising a transduction enhancing agent and, subsequently, with a composition comprising an oncolytic virus. Bladder treatment compositions comprising a transduction enhancing agent and an oncolytic virus are also described.
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申请公布号 |
US2009068151(A1) |
申请公布日期 |
2009.03.12 |
申请号 |
US20080284734 |
申请日期 |
2008.09.23 |
申请人 |
CELL GENESYS, INC. |
发明人 |
RAMESH NAGARAJAN;FREY DAVID;MEMARZADEH BAHRAM;YU DECHAO |
分类号 |
A61K35/76;A61K9/00;A61K31/337;A61K31/7024;A61K45/06;A61K47/10;A61K47/26;A61K48/00;A61P35/04 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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