VIRUS-SPECIFIC MIRNA SIGNATURES FOR DIAGNOSIS AND THERAPEUTIC TREATMENT OF VIRAL INFECTION

摘要

The present invention related to miRNA signatures and diagnostic and therapeutic applications of miRNA signatures. The miRNA signatures are defined by a test sample miRNA profile relative to an appropriate control miRNA profile. In some embodiments, the test sample is a sample isolated, obtained or derived from a virus- infected cell or organism. The present invention further relates to the use of miRNA signatures in the identification of draggable targets and antiviral agents. Kits and compositions are also provided.