发明名称 1,2,4,5-Tetrahydro-3H-benzazepine compounds, a process for their preparation and pharmaceutical compositions containing them
摘要 Compounds of formula (I): wherein: R1 represents a hydrogen atom or a group selected from cycloalkyl, benzyl and optionally substituted alkyl, R2, R3, R4 and R5 each represent a hydrogen atom or a hydroxy, methyl, -OSO2R10, -OCOR10 or optionally substituted alkoxy group, or R2 and R3, or R3 and R4, or R4 and R5 together form a group -O-(CH2)q-O-, -O-CH-CH-O- or -O-CH-CH-, R6, R7, R8 and R9 each represent a hydrogen atom or an alkoxy group, or R6 and R7, or R7 and R8, or R8 and R9 together form a group -O-(CH2)q-O--, R10 represents a group selected from linear or branched C1-C6alkoxy, NR11R'11 and optionally substituted alkyl, R11 and R'11 each represent a hydrogen atom or an alkyl group, or R11 and R'1 together with the nitrogen atom carrying them form an optionally substituted, monocyclic or bicyclic, nitrogen-containing heterocycle, X represents O, NH or CH2, m and p each represent 0 or 1, n and q each represent 1 or 2, in racemic form or in the form of optical isomers,and also addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in treating various pathologies.
申请公布号 US2009069296(A1) 申请公布日期 2009.03.12
申请号 US20080283110 申请日期 2008.09.09
申请人 LES LABORATOIRES SERVIER 发明人 PEGLION JEAN-LOUIS;GOUMENT BERTRAND;DESSINGES AIMEE;CAIGNARD PASCAL;VILAINE JEAN-PAUL;THOLLON CATHERINE;VILLENEUVE NICOLE;CHIMENTI STEFANO
分类号 C07D223/16;A61K31/55 主分类号 C07D223/16
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