发明名称 MODIFIED POLYMERASES AND ATTENUATED VIRUSES AND METHODS OF USE THEREOF
摘要 Compositions and methods involving modified viral polymerases with one or more substitutions of different amino acids at conserved regions of the polymerase result in enzymes with varying rates and fidelity of replication A universally applicable polymerase mechanism based strategy for the production of attenuated viruses and anti-viral vaccines is also disclosed
申请公布号 WO2008140622(A3) 申请公布日期 2009.03.12
申请号 WO2007US88775 申请日期 2007.12.24
申请人 THE PENN STATE RESEARCH FOUNDATION;CAMERON, CRAIG, E.;ARNOLD, JAMIE;CASTRO, CHRISTIAN 发明人 CAMERON, CRAIG, E.;ARNOLD, JAMIE;CASTRO, CHRISTIAN
分类号 C12N7/04;C12P21/06 主分类号 C12N7/04
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