AMORPHOUS OXCARBAZEPINE AND THE PRODUCTION THEREOF
摘要
Oxcarbazepine compositions of enhanced bioavailability are described that contain oxcarbazepine with at least one solubility-enhancing polymer. Described methods to produce the bioenhanced products include solvent spray drying. One aspect of the method includes the steps of providing a mixture comprising oxcarbazepine, a solubility-enhancing polymer and a single solvent, a solvent blend or solvent/non-solvent blend removing and then evaporating the mixture to form amorphous oxcarbazepine.
申请公布号
WO2008092046(A3)
申请公布日期
2009.03.12
申请号
WO2008US51975
申请日期
2008.01.25
申请人
ISP INVESTMENTS INC.;BRZECZKO, ALBERT, WALTER;DONEY, JOHN, ALFRED