The invention relates to immunostimulatory RNA oligonucleotides (ORN). In particular the ORN have an immunostimulatory ORN motif directly or indirectly flanked by a 3' poly G motif and optionally a 5' poly-G motif. The invention also relates to methods including therapeutic methods and screening methods and related kits for use of the ORN.
申请公布号
WO2008139262(A8)
申请公布日期
2009.03.12
申请号
WO2007IB04593
申请日期
2007.10.26
申请人
COLEY PHARMACEUTICAL GMBH;JURK, MARION;VOLLMER, JOERG;UHLMANN, EUGEN