发明名称 |
Isolated Fungal Promoters and Gene Transcription Terminators and Methods of Protein and Chemical Production in a Fungus |
摘要 |
The present invention encompasses isolated gene regulatory elements and gene transcription terminators that are differentially expressed in a native fungus exhibiting a first morphology relative to the native fungus exhibiting a second morphology. The invention also encompasses a method of utilizing a fungus for protein or chemical production. A transformed fungus is produced by transforming a fungus with a recombinant polynucleotide molecule. The recombinant polynucleotide molecule contains an isolated polynucleotide sequence linked operably to another molecule comprising a coding region of a gene of interest. The gene regulatory element and gene transcription terminator may temporally and spatially regulate expression of particular genes for optimum production of compounds of interest in a transgenic fungus.
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申请公布号 |
US2009068723(A1) |
申请公布日期 |
2009.03.12 |
申请号 |
US20080257261 |
申请日期 |
2008.10.23 |
申请人 |
BATTELLE MEMORIAL INSTITUTE |
发明人 |
DAI ZIYU;LASURE LINDA L.;MAGNUSON JON K. |
分类号 |
C12N1/21;C12N15/00;C12N15/11 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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