POLYETHYLENE GLYCOL MODIFIED INTERFERON ALPHA 2B AND PREPARATION METHOD AND APPLICATIOINS THEREOF

摘要

Provided are mono-modified interferon alpha 2b by Y-type branched polyethylene glycol at the specific lysine position and the preparation method thereof. The pegylated interferon alpha 2b can be used for manufacture of pharmaceutical composition for treating diseases such as viral infection like hepatitis C etc.