发明名称 |
GENE INVOLVED IN IMMORTALIZATION OF HUMAN CANCER CELL AND USE THEREOF |
摘要 |
<p>The present invention provides a gene related to cancer cell immortalization (an immortalization determining gene) and a process that is useful for selective cancer treatment targeting a cancer cell having the gene. The present invention determines an immortalized cancer cell using a polynucleotide having a base sequence of at least 15 bases that specifically hybridizes with a continuous base sequence of at least 15 bases within any one of abase sequences represented by SEQ ID Nos. 1 to 13. In the foregoing process, the polynucleotide is used as a primer or probe for detecting an immortalization determining gene that exhibits high expression specifically in an immortalized cancer cell.</p> |
申请公布号 |
EP2034017(A1) |
申请公布日期 |
2009.03.11 |
申请号 |
EP20070767074 |
申请日期 |
2007.06.08 |
申请人 |
KABUSHIKI KAISHA YAKULT HONSHA |
发明人 |
NISHIYAMA, MASAHIKO;HIYAMA, KEIKO;TANIMOTO, KEIJI;MASUKO, NORIO |
分类号 |
C12N15/00;A61K31/7088;A61P35/00;A61P43/00;C07K16/32;C12N15/09;C12Q1/68;G01N33/15;G01N33/50;G01N33/574 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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