Pravastatin pharmaceutical formulations and methods of their use

摘要

The present invention relates to formulations comprising a therapeutically effective amount of pravastatin, or a pharmaceutially acceptable salt thereof The present formulations are designed to prevent inactivation of pravastatin in the stomach, limit systemic exposure of the body to pravastatin, and maximize hepatic-specific absorption of the drug. The formulations of the present invention are particularly useful for treating and/or preventing conditions that are benefited by decreasing levels of lipids and/or cholesterol in the body.