发明名称 |
METHOD, MATERIALS AND APPARATUS FOR INVESTIGATING ASTHMA USING DUST MITE ALLERGEN |
摘要 |
The present invention comprises a method, materials and apparatus for investigating asthma in humans using dust mite allergen. The dust mite allergen is prepared to be of a controlled size such that particles are respirable, effectively aerosolized, and deliver a significant amount of allergen. The dust mite allergen is applied in a controlled manner within an environmental exposure chamber to elucidate the etiological links between dust mite allergen concentration and asthma response in humans. The environmental exposure chamber is specially-designed to promote homogeneity of allergen concentration. Preferably, the dust mite allergen preparation comprises particles having an average diameter of less than 25 microns, and more preferably 5-10 microns. Correlation between aerosolized particle count and allergen concentration enables "real-time" allergen concentration estimates without the use of expensive and time-consuming assay techniques. |
申请公布号 |
EP2032041(A1) |
申请公布日期 |
2009.03.11 |
申请号 |
EP20070719912 |
申请日期 |
2007.06.07 |
申请人 |
ALLIED RESEARCH INTERNATIONAL INC. |
发明人 |
PATEL, PIYUSH, RANCHODBHAI;SALAPATEK, ANNE, MARIE |
分类号 |
A61B10/00;A61K49/00 |
主分类号 |
A61B10/00 |
代理机构 |
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