Process for resolving a mixture of alkyl ester enantiomers using an enzyme
摘要
A process for resolving a mixture of alkyl ester enantiomers comprising contacting the mixture with an enzyme effective to preferentially promote the hydrolysis of one of the enatiomers characterized in that the contacting is conducted in the presence of a buffer.
申请公布号
EP2033654(A1)
申请公布日期
2009.03.11
申请号
EP20080075882
申请日期
2004.04.16
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
MCPHEE, FIONA;CAMPBELL, JEFFREY ALLEN;LI, WENYING;D'ANDREA, STANLEY;ZHENG, ZHIZHEN BARBARA;GOOD, ANDREW CHARLES;CARINI, DAVID J.;JOHNSON, BARRY L.;SCOLA, PAUL MICHAEL;BOY, KENNETH M.
