发明名称 FUNCTIONALLY RECONSTRUCTED ADJUVANT-CONTAINING VIRUS MEMBRANES
摘要 FIELD: medicine; biotechnologies. ^ SUBSTANCE: substance of invention involved reconstructed virus membrane with lipid bilayer containing fused virus protein and amphiphilic adjuvant represented with lipopeptide. Further invention refers to production procedures of reconstructed virus membranes manifesting fused membrane activity, that are lipid bilayer membranes preferably containing natural virus lipids, fused virus protein, optionally, one or more additional antigens and amphiphilic adjuvants. Besides invention refers to pharmaceutical compositions containing these reconstructed virus membranes. ^ EFFECT: intensified immune response. ^ 13 cl, 6 ex, 1 tbl, 10 dwg
申请公布号 RU2348428(C2) 申请公布日期 2009.03.10
申请号 RU20060101394 申请日期 2004.06.18
申请人 BESTEVIL KHOLDING B.V. 发明人 STEGMANN ANTONIUS JOKHANNES;VILSKHUT JAN KRISTIAN;VAN BERKUM JOKHANNES KHENRIKUS GERARDUS
分类号 A61K39/39;A61K9/00;A61K9/133;A61K39/12;A61K39/145;A61P31/00;A61P31/12;C07K14/11;C07K16/10 主分类号 A61K39/39
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