发明名称 METHOD OF VALSARTAN OBTAINMENT
摘要 FIELD: chemistry. ^ SUBSTANCE: compound of general formula IIa or its salt, where R1 is hydrogen or protection group of tetrazol, undergoes reaction with compound of formula or its salt, where R2 is hydrogen or carboxy protection group, under conditions of reduction amination, with further acylation of obtained compound of formula or its salt by compound of formula , where R3 is the group to be separated; and with removal of protection groups if required. ^ EFFECT: new compounds with useful biological properties. ^ 12 cl, 11 ex
申请公布号 RU2348619(C2) 申请公布日期 2009.03.10
申请号 RU20050112444 申请日期 2003.09.22
申请人 NOVARTIS AG 发明人 DENNI-DISHER DONAS'ENN;KHIRT KHANS;NEVILLE DAN;ZEDEL'MAJER GOTTFRID;SHNIDER ANITA;DERR'EN NADIN;KAUFMANN DANIEL'
分类号 C07D257/04 主分类号 C07D257/04
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