发明名称 Naphthyl compounds, intermediates, processes, compositions, and methods
摘要 The present invention is a method for treating uterine fibroid disease using a compound of formula I wherein R1 is -H, -OH, -O(C1-C4 alkyl), -OCOC6H5, -OCO(C1-C6 alkyl), or -OSO2(C4-C6 alkyl); R2 is -H, -OH, -O(C1-C4 alkyl), -OCOC6H5, -OCO(C1-C6 alkyl) or -OSO2(C4-C6 alkyl); n is 2 or 3; and R3 is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, or 1-hexamethyleneimino; or a pharmaceutically acceptable salt thereof.
申请公布号 US7501441(B1) 申请公布日期 2009.03.10
申请号 US19940309525 申请日期 1994.09.20
申请人 ELI LILLY AND COMPANY 发明人 BRYANT HENRY U.;CULLINAN GEORGE J.;DODGE JEFFREY A.;FAHEY KENNAN J.;JONES CHARLES D.;LUGAR CHARLES W.;MUEHL BRIAN S.
分类号 A61K31/445;C07D295/08;A61K31/13;A61K31/135;A61K31/40;A61K31/4453;A61K31/535;A61K31/5375;A61K31/55;A61P3/02;A61P3/06;A61P13/02;A61P15/00;A61P15/12;A61P19/10;A61P35/00;A61P43/00;C07C211/19;C07C213/08;C07C217/18;C07C303/26;C07C309/65;C07D207/06;C07D207/08;C07D211/22;C07D295/088;C07D295/092 主分类号 A61K31/445
代理机构 代理人
主权项
地址