| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: present invention refers to new compounds described by formula in which radical and symbol values are specified in the patent claim, and their pharmaceutically acceptable salts. These compounds inhibit tompomyosine-related kinases (Trk), and can find application in treating a malignant growth, such as breast cancer, rectal cancer and prostate cancer. Also, the invention relates to a method for producing these compounds, a based pharmaceutical composition and to methods of application thereof. ^ EFFECT: preparation of the pharmaceutical composition which can find application in treating a malignant growth. ^ 18 cl, 134 ex |
