发明名称 METHOD FOR THE PREDICTION OF PREECLAMPSIA AND OTHER DISEASES
摘要 The invention disclosed is a process for determining the cytoprotective activity of plasma that prevents the destruction of endothelial cells and forestalls the development of a number of diseases such as atherosclerosis, preeclampsia, edema, nephrotic syndrome, and stroke. The present invention includes a method of diagnosing a patient's proclivity to develop a disease having a correlation to a reduction in the concentration of pI 5.6 albumin in the plasma by determinin g a value indicative of the concentration of the pI. 5.6 albumin that is not bound to VLDL ("non-VLDL-bound pI 5.6 albumin") in the patient's blood serum. The preferre d embodiment of the process utilizes in vitro methods to obtain an indicator o f the non-VLDL-bound pI. 5.6 albumin instead of directly measuring the concentrati on of the non-VLDL-bound pI 5.6 albumin.
申请公布号 CA2404218(C) 申请公布日期 2009.03.10
申请号 CA20012404218 申请日期 2001.03.13
申请人 ARBOGAST PHARMACEUTICALS, INC. 发明人 ARBOGAST, BRADLEY W.
分类号 G01N33/66;G01N33/92;C12Q1/26;C12Q1/28;C12Q1/527;G01N33/50;G01N33/52;G01N33/53;G01N33/68 主分类号 G01N33/66
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