发明名称 |
Method for bisulfite treatment |
摘要 |
The invention is related to the detection of a methylated cytosine in a nucleic acid wherein guanidinium hydrogen sulfite is used for the preparation of a solution containing guanidinium ions and sulfite ions and subsequent modification of the nucleic acid. Thereby, a non-methylated cytosine is converted to uracil. The invention further discloses kits for performing the methods of the invention.
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申请公布号 |
US7501240(B2) |
申请公布日期 |
2009.03.10 |
申请号 |
US20040573215 |
申请日期 |
2004.12.01 |
申请人 |
ROCHE MOLECULAR SYSTEMS, INC. |
发明人 |
BIRKNER CHRISTIAN;MARKERT-HAHN CHRISTINE;VON DER ELTZ HERBERT |
分类号 |
C12Q1/68;C07H21/00;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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