发明名称 |
Recombinant infectious laryngotracheitis virus and uses thereof |
摘要 |
The present invention provides a recombinant, attenuated infectious laryngotracheitis virus comprising the infectious laryngotracheitis viral genome which contains a deletion in the glycoprotein gG gene. This attenuated virus is useful as a vaccine against infectious laryngotracheitis virus. The present invention also provides a recombinant, attenuated infectious laryngotracheitis virus comprising the infectious laryngotracheitis viral genome which contains a deletion in the US2 gene, UL47-like gene, ORF4 gene or glycoprotein g60 gene. The present invention also provides a method for distinguishing chickens or other poultry vaccinated with a recombinant infectious laryngotracheitis virus which produces no glycoprotein gG from those infected with a naturally-occurring infectious laryngotracheitis virus.
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申请公布号 |
US7501491(B2) |
申请公布日期 |
2009.03.10 |
申请号 |
US20080047787 |
申请日期 |
2008.03.13 |
申请人 |
SCHERING-PLOUGH ANIMAL HEALTH CORP. |
发明人 |
WILD MARTHA A.;COCHRAN MARK D. |
分类号 |
C07K14/00;A61K39/00;A61K39/12;A61K39/245;C07K14/03;C12N7/01;C12N15/09;C12N15/38;C12N15/869;C12P21/00 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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