摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention concerns chemistry of adamantane derivatives, particularly new method of obtaining N,N-dialkyl-substituted amides of adamantylalkylcarboxylic acids of the general formula ^ ^ which can be of interest as semiproducts in synthesis of some bioactive substances with antivirus effect. Method involves interaction of adamantane derivative with carboxylic acid dialkylamide, where 1,3-dehydroadamantane is used as adamantane derivative, and N,N-dimethylacetamide, N,N-diethylacetamide, N-acethylpiperidine, N-propionylpiperidine, N-(2-methyl)propionylpiperidine are used as carboxylic acid dialkylamides, and process runs at reagent mol ratio of 1:2-3 respectively, in original carboxylic acid dialkylamide medium at 120-130°C for 5-6 hours. ^ EFFECT: alternative method of obtaining compounds of the claimed structural formula, with omitted stage of obtaining adamantylalkylcarboxylic acids. ^ 5 ex
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