PYRASOLE[3,4-b]PYRIDINE COMPOUNDS AND THEIR APPLICATION AS PHOSPHODIESTERASE INHIBITORS

摘要

FIELD: chemistry. ^ SUBSTANCE: invention concerns compound of formula (I) where Ry is , or its pharmaceutically acceptable salts. These compounds have phosphodiesterase (PDE) inhibition effect, particularly for PDE-4. Additionally invention claims application of compound of the formula (I) or its pharmaceutically acceptable salt in manufacturing of medicine for treatment and/or prevention of cognitive ability depression or disorder of humans, e.g. of chronic neurological disorder, such as Alzheimer's disease. ^ EFFECT: enhanced efficiency of composition and treatment method. ^ 17 cl, 21 tbl, 191 ex