| 发明名称 |
VR1 VANILLOID RECEPTOR ANTAGONISTS WITH A IONONIC SUBSTRUCTURE. |
| 摘要 |
<p>The invention provides compounds of formula (I), wherein Y, R, n and X are as defined in the description, a process for their preparation and pharmaceutical compositions containing them. The compounds of formula (I) inhibit the Transient Receptor Potential Vanilloid 1 (TRPV1 ), which plays a pivotal role in the development of post-inflammatory analgesia, therefore they can be used as analgesic and anti-inflammatory drugs.</p> |
| 申请公布号 |
MX2009000365(A) |
申请公布日期 |
2009.03.09 |
| 申请号 |
MX20090000365 |
申请日期 |
2007.07.02 |
| 申请人 |
PHARMESTE S.R.L. |
发明人 |
BOREA, PIER, ANDREA;BARALDI, PIER GIOVANNI;GEPPETTI, PIERANGELO;PAVANI, MARIA GIOVANNA;FRUTTAROLO, FRANCESCA;TREVISANI, MARCELLO |
| 分类号 |
C07D217/02;C07C233/11;C07C233/15;C07C233/28;C07D213/75;C07D217/22 |
主分类号 |
C07D217/02 |
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