| 发明名称 |
Mutant herpes simplex viruses comprising nucleic acid encoding a nitroreductase |
| 摘要 |
An herpes simplex virus wherein the herpes simplex virus genome comprises nucleic acid encoding a nitroreductase (NTR) is disclosed. Disclosed herpes simplex viruses are indicated to be useful in the treatment of cancer which may involve gene directed enzyme prodrug therapy.
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| 申请公布号 |
US7498161(B2) |
申请公布日期 |
2009.03.03 |
| 申请号 |
US20040579606 |
申请日期 |
2004.11.17 |
| 申请人 |
CRUSADE LABORATORIES LIMITED |
发明人 |
BROWN SUSANNE MOIRA;DUNN PAUL |
| 分类号 |
C12N7/00;A61K35/76;A61K48/00;C12N15/113;C12N15/869 |
主分类号 |
C12N7/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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