发明名称 |
THERAPEUTIC USE OF AN AGENT THAT STIMULATES NO OR PROSTACYCLIN PRODUCTION AND DELIVERY DEVICE |
摘要 |
Vascular endothelial growth factor (VEGF) has utility in the treatment of intimal hyperplasia, hypertension and atherosclerosis, and of conditions susceptible to treatment with agents that produce nitric oxide or prostacyclin. Instead of VEGF, an equivalent agent such as an agonist of VEGF receptors may be given, as may nucleic acid encoding such an agonist. The agent may successfully be administered via the adventitial surface of a blood vessel, e.g. using a device which defines a reservoir between the body wall and the vessel's adventitial surface, the reservoir being at least part-filled by a pharmaceutical formulation containing the agent to be delivered.
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申请公布号 |
CA2270286(C) |
申请公布日期 |
2009.03.03 |
申请号 |
CA19972270286 |
申请日期 |
1997.11.03 |
申请人 |
EUROGENE LIMITED |
发明人 |
YLA-HERTTUALA, SEPPO;BARKER, STEPHEN GEORGE EDWARD;MARTIN, JOHN FRANCIS |
分类号 |
A61K9/00;A61K48/00;A61B17/11;A61F2/00;A61F2/06;A61K31/711;A61K38/18;A61K38/19;A61K38/22;A61K38/44;A61K45/00;A61L31/14;A61L31/16;A61P9/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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