发明名称 |
Detection of biochemical interactions on a biosensor using tunable filters and tunable lasers |
摘要 |
An apparatus and method for detection of peak wavelength values of colorimetric resonant optical biosensors using tunable filters and tunable lasers is provided. Biomolecular interactions may be detected on a biosensor by directing collimated white light towards a surface of the biosensor. Molecular binding on the surface of the biosensor is indicated by a shift in the peak wavelength value of reflected or transmitted light from the biosensor, while an increase in the wavelength corresponds to an increase in molecular absorption. A tunable laser light source may generate the collimated white light and a tunable filter may receive the reflected or transmitted light and pass the light to a photodiode sensor. The photodiode sensor then quantifies an amount of the light reflected or transmitted through the tunable filter as a function of the tuning voltage of the tunable filter.
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申请公布号 |
US7497992(B2) |
申请公布日期 |
2009.03.03 |
申请号 |
US20030434015 |
申请日期 |
2003.05.08 |
申请人 |
SRU BIOSYSTEMS, INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
CUNNINGHAM BRIAN T.;LI PETER Y.;CHANG-HASNAIN CONSTANCE;MATEUS CARLOS |
分类号 |
C12M1/34;C12M3/00;G01N21/00;G01N21/39;G01N21/45;G01N21/75;G01N33/50;G01N33/53;G01N33/543 |
主分类号 |
C12M1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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