发明名称 |
USE OF TRANSCRIPTOME-MODIFYING AGENTS AND CHEMOTHERAPY OR RADIOTHERAPY AGAINST CANCER. |
摘要 |
The invention relates to the use of transcriptome-modifying agents in order to prevent malignant cells from undergoing the necessary genetic changes in order to combat cell insult and survive chemotherapy or radiotherapy. Said combination of transcriptome-modifying agents comprises agents that inhibit the DNA methylation machinery plus a substance that inhibits histone deacetylation. The invention relates to a treatment kit which involves the administration of an effective dose of hydralazine and valproic acid or a salt of same in the case of magnesium valproate, which is intended for use with radiotherapy or chemotherapy in the treatment of patients cancer.
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申请公布号 |
MX2008006358(A) |
申请公布日期 |
2009.03.02 |
申请号 |
MX20080006358 |
申请日期 |
2008.05.16 |
申请人 |
UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO |
发明人 |
ALFONSO DUENAS GONZALEZ;LUIS ESTRADA FLORES |
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