| 摘要 |
<p>The invention relates to a bioproduct as hydrogel consisting of 1...5% carbomer, 10...20% native collagen type I and III having an average molecular weight of 300...250 kDa, 1...5% alpha- or kappa-elastin as soluble peptides having an average molecular weight of 50...150 kDa, 1...6% glycosaminoglycans selected from chondroitin sulphate, dermatan sulphate and hyaluronic acid, 5...10% a 50...70% alcohol extract of Equisetum arvense, 5...10% a 50...70% alcohol extract of Alchillea millefolium, 0.1...0.5% nipagin and nipasol and, for the remainder up to 100% distilled water, the percentage being expressed by weight, and to a process for preparing the same, consisting in mixing 40 parts of composition (I) made of a carbomer gel having a concentration of 1...5%, prepared in distilled water, with 0.1...0.3% nipagin-nipasol mixture, which is left to rest for 24 hours, controlling the mixture to a pH=6...7 with a 0.2 triethanol amine solution and admixing 10...30 parts of composition (II) as viscous solution having a pH=6...7, made of 60...90% solution of collagen type I and III in a concentration of 0.5...1% and an average molecular weight of 300...350 kDa, 5...10% alpha- or kappa-elastin solution in a concentration of 0.1...0.5% and an average molecular weight of 50...150 kDa and 5...10% glycosaminoglycan solution in a concentration of 0.1...0.5%, and finally mixing it with 10...30 parts of composition (III) made of 50% a 50...70% alcohol extract of Equisetum arvense in a concentration of 1...5% and 50% a 50...70% alcohol extract of Alchillea millefolium in a concentration of 1...5%, at the temperature of 37A C, the mixture being afterwards cooled down to the ambient temperature and the resulting hydrogel being conditioned in plastic jars of 30...100 ml.</p> |
