发明名称 |
QUINOLINE INTERMEDIATES OF RECEPTOR TYROSINE KINASE INHIBITORS AND THE SYNTHESIS THEREOF |
摘要 |
QUINOLINE INTERMEDIATES OF RECEPTOR TYROSINE KINASE INHIBITORS AND THE SYNTHESIS THEREOF This invention is directed to methods of preparing 4-substituted quinoline compounds as intermediates in the manufacture of receptor tyrosine kinase inhibitors and intermediate compounds used in the methods thereof, wherein the 4-substituted quinoline compound has the general formula (I); and wherein substitutions at LG", PG, A, G, RI and R4 are set forth in the specification.
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申请公布号 |
SG149817(A1) |
申请公布日期 |
2009.02.27 |
申请号 |
SG20090000787 |
申请日期 |
2005.01.14 |
申请人 |
WYETH |
发明人 |
WANG, YOUCHU;WARREN, CHEW;PAPAMICHELAKIS, MARIA |
分类号 |
A61K31/47;C07D215/12;C07D215/54;C07D295/155;C07D413/04 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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