发明名称 Pyrrolo Pyrimidines as Agents for the Inhibition of Cystein Proteases
摘要 The invention provides compounds of Formula I or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g. various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
申请公布号 US2009054467(A1) 申请公布日期 2009.02.26
申请号 US20080237896 申请日期 2008.09.25
申请人 发明人 BETSCHART CLAUDIA;HAYAKAWA KENJI;IRIE OSAMU;SAKAKI JUNICHI;IWASAKI GENJI;LATTMANN RENE;MISSBACH MARTIN;TENO NAOKI
分类号 A61K31/52;A61K31/519;A61K31/5377;A61K31/551;A61P9/00;A61P9/10;A61P11/00;A61P19/02;A61P19/10;A61P29/00;A61P31/00;A61P35/00;A61P35/04;A61P37/02;A61P37/06;A61P43/00;C07D473/00;C07D487/04;C07D519/00 主分类号 A61K31/52
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